Suitable for leak detection in soft IV bags used for large-volume parenteral (LVP) solutions. It detects a wide range of sealing issues, including micro-holes larger than 0.1μm, as well as defects along the bag’s welded seams, the port area, and the tube connections. This type of inspection is important to ensure that the container maintains sterility and structural integrity throughout its shelf life.
Soft IV bags are first aligned at regular intervals on the infeed conveyor (1). An industrial robot transfers each bag one by one into the inspection section (2), which uses segmented conveyor belts to guide the flow. Multiple inspection stations are arranged along this path, and each can be adjusted to focus on specific areas of the bag, ensuring a thorough, 360-degree leak check across all sealing and structural points.
Once the inspection is complete, any bags that fail are automatically removed by the rejection unit (3), while those that pass continue on the outfeed conveyor (4). (Refer to Fig 1)
High Voltage Leak Detection (HVLD) works by applying a high-frequency, high-voltage signal between two external electrodes placed on opposite sides of the container. These electrodes do not make direct contact with the liquid; instead, a capacitive field is formed between the electrodes and the solution through the container wall. This setup creates two capacitors: C1 and C2. The solution itself acts as a resistor (R), and its conductivity should be ≥1.2 μS to ensure proper signal transmission and accurate detection.
By comparing the current levels from these two scenarios, the leak testing system can accurately determine whether a container is intact or leaking.
It refers to the process of verifying that pharmaceutical containers are free from damage, cracks, or incomplete seals. This ensures that the product remains sterile and protected throughout its shelf life.
Standard techniques include High Voltage Leak Detection (HVLD) and Vacuum Decay. Both are non-destructive methods widely used in pharmaceutical production to detect micro-leaks and ensure sealing reliability.
HVLD is one of the most effective options. It offers high sensitivity and fast detection speeds, making it ideal for inspecting glass containers and flexible packaging like IV bags without causing any damage.
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