Hunan Zhengzhong Pharmaceutical Machinery Co., Ltd.
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Leak Testing Machines

Reliable Equipment for Container Closure Integrity Testing (CCIT)

In 2012, Z-ZONE introduced China’s first leak testing machine fully developed in-house, including the mechanical structure, electrical system, and high-frequency high-voltage power supply. To date, we remain the only domestic manufacturer with an independently developed high-voltage power system for this type of equipment. We also participated in drafting the Chinese industry standard for leak testers (Standard No. JB/T20170-2016).

IV Bag Leak Testing Machine
IV Bag Leak Testing Machine

Suitable for leak detection in soft IV bags used for large-volume parenteral (LVP) solutions. It detects a wide range of sealing issues, including micro-holes larger than 0.1μm, as well as defects along the bag’s welded seams, the port area, and the tube connections. This type of inspection is important to ensure that the container maintains sterility and structural integrity throughout its shelf life.

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Ampoule/Vial Leak Testing Machine
Ampoule/Vial Leak Testing Machine

Used to inspect ampoules, vials, and oral liquid bottles for potential leakage. It accurately detects micro-holes and cracks located in critical areas such as the seal, body, and bottom of the container, ensuring that each unit meets container closure integrity standards before release.

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BFS Ampoule Leak Testing Machine
BFS Ampoule Leak Testing Machine

Designed for comprehensive leak inspection of multi-unit plastic ampoules produced via Blow-Fill-Seal (BFS) technology. Our BFS ampoule leak testing system can also be adapted to test similar strip-packaged products such as ophthalmic solutions and oral liquids, ensuring packaging integrity across a variety of container types.

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Prefilled Syringe Leak Testing Machine
Prefilled Syringe Leak Testing Machine

Suitable for leak testing for prefilled syringes; focuses on identifying micro-holes and cracks in the barrel, especially around joint lines and the plunger area. This leak tester is also suitable for prefilled syringes and other injectable containers that require high-sensitivity CCI (Container Closure Integrity) evaluation.

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BFS Vacuum Decay Leak Testing Machine
BFS Vacuum Decay Leak Testing Machine
  • Designed for non-destructive integrity testing of BFS plastic ampoule containers filled with pharmaceutical products
  • Supports 100% online and offline inspection, even under high-speed production conditions
  • Leak detection is performed inside a sealed test chamber with a pressure differential
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Performance and Functionality

Our leak testing machines are equipped with a modern automation control system that supports automatic bottle feeding, leak testing, and sorting. This reduces the risk of errors and contamination associated with manual handling. The testing system achieves a stable testing speed of up to 600 bottles per minute.

Supporting Quality and Safety

These inspection systems allow real-time process monitoring, along with data logging and analysis, making it easier for pharmaceutical producers to maintain quality control and traceability. By analyzing inspection results, manufacturers can identify potential issues early and make timely adjustments to improve production quality.

Additional safety features, including protective enclosures and emergency stop buttons, are built into the structure. The design also addresses both electrical and mechanical safety standards to ensure stable operation and reduce safety risks during use. Leak testers developed by Z-ZONE are currently used in more than ten countries, including Russia, Indonesia, Iran, Colombia, Pakistan, and Malaysia. They support pharmaceutical companies in maintaining container integrity while improving efficiency and consistency during quality control.

Frequently Asked Questions

How do non-destructive leak testing machines work without damaging the container?

Most models rely on high voltage leak detection (HVLD), a non-contact method that applies electrical signals through external electrodes. Since there's no direct contact with the liquid or the container interior, there's no risk of contamination during inspection.

Is it easy to operate non-destructive leak testing system?

Yes. Each unit comes with an HMI control panel designed for smooth operation. Even staff with minimal training can manage inspections effectively, thanks to clear visual indicators and intuitive controls that guide them through each step.

What’s the smallest defect size that can be detected?

The non-destructive leak testing equipment is capable of identifying cracks and pinholes as small as 0.2 microns, depending on the container type and conductivity of the liquid.

What type of defects can be detected in IV bags?

The IV bag leak tester is designed to spot leaks caused by micro-holes (≥0.1μm), poor sealing at welded edges, and weak points around ports or outlet tubes. It’s commonly used to inspect soft bags filled with large-volume parenteral.

Want to speak directly to our specialists?

If you’re looking to elevate the safety and quality of your pharmaceutical packaging, our visual inspection machines deliver the accuracy and reliability your production line needs.
Let’s talk about how we can tailor a solution for your specific containers and inspection standards.

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Test Methods
Visual Image Processing
Visual Image Processing
Vacuum Decay
Vacuum Decay
High Voltage Leak Detection (HVLD)
High Voltage Leak Detection (HVLD)
Filter Applications
Filter Applications
Liquid Dosage
Liquid Dosage

We provide advanced automatic visual inspection and leak testing systems tailored for liquid pharmaceutical products, including injectables, eye drops, and oral solutions in ampoules, vials, prefilled syringes, and bottles.

Freeze-Dried Powder
Freeze-Dried Powder

We provide integrated automatic visual inspection and leak testing solutions for lyophilized (freeze-dried) powder products in vials (2–30 ml), suitable for both molded and tubular vial formats.

  • Since 1967
    1967

    Since 1967

  • 35000 square meters production base
    35000

    35000 square meters production base

  • More than 30 production lines
    30+

    More than 30 production lines

  • 1500 cooperative clients
    1500

    1500 cooperative clients

Products
  • Visual Inspection Machines
  • Leak Testing Machines
  • Visual Inspection & Leak Testing Machine
Test Methods
  • Visual Image Processing
  • Vacuum Decay
  • High Voltage Leak Detection (HVLD)
Applications
  • Liquid Dosage
  • Freeze-Dried Powder
Contact Us
zzoneinspection@gmail.com
+86-731-88906436
+86-18692213322 (Sabrina Wang)
+86-13786180170 (Cici Li)