Hunan Zhengzhong Pharmaceutical Machinery Co., Ltd.
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Leak Testing Machines
  • BFS Vacuum Decay Leak Testing Machine
  • BFS Vacuum Decay Leak Testing Machine
  • BFS Vacuum Decay Leak Testing Machine
  • BFS Vacuum Decay Leak Testing Machine
BFS Vacuum Decay Leak Testing Machine
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Container Closure Integrity Testing (CCIT)

BFS Vacuum Decay Leak Testing Machine

Non-destructive integrity testing equipment for detecting leaks in blow-fill-seal (BFS) containers
Technical Specifications
  • Applicable container: BFS plastic ampoules (clean and dry)
  • Max. size of container: 135×900mm
  • Machine dimensions (L×W×H): 3000×1900×2200mm
  • Power supply: 380V 3 phase 50Hz
Highlights
  • Designed for non-destructive integrity testing of BFS plastic ampoule containers filled with pharmaceutical products
  • Supports 100% online and offline inspection, even under high-speed production conditions
  • Leak detection is performed inside a sealed test chamber with a pressure differential
  • Determines container integrity by measuring achieved pressure levels and monitoring pressure changes during the test cycle
  • Capable of identifying micro leaks, seal failures, and cracks that may compromise sterility
  • Requires test containers to be clean and dry for accurate results
  • Suitable for installation in Class C and D cleanroom environments during less critical aseptic processing stages
Regulatory Compliance & Industry Standards
  • All validation and qualification processes are fully aligned with current Good Manufacturing Practice (GMP) guidelines.
  • Materials and construction methods meet the hygiene and quality standards required in pharmaceutical production environments.
  • The testing system features a polycarbonate safety shield to prevent injuries from accidental contact or compression.
  • Its clean design minimizes the risk of contamination by eliminating hard-to-clean corners or areas where residue might accumulate.
  • A clear separation is maintained between the technical components and the product-handling zone to ensure controlled processing conditions.
Features
  • Automatic feeding and unloading streamline the handling of BFS containers during the testing process
  • High sensitivity enables the detection of even the slightest leaks with precision
  • Delivers fast, reliable, and repeatable test results for consistent quality assurance
  • Utilizes a non-invasive, non-destructive method that preserves product integrity
  • Enhanced HMI offers intuitive controls and smooth system interaction
  • Built-in self-diagnostic capabilities improve operational reliability
  • Hygienic design with no hidden corners simplifies cleaning procedures
  • All moving parts are easily accessible, making routine maintenance more efficient
  • Tracks and stores historical production, testing, event, and alarm data for traceability
  • Real-time display of leak testing curves on the HMI helps operators monitor performance instantly
Principle of Vacuum Decay Leak Testing

Vacuum-based leak testing is carried out using 30 chambers, each designed to perform non-destructive integrity testing on sealed pharmaceutical containers. Once capped, the containers are transferred via a conveyor, then spaced apart by a screw feed system and positioned beneath the inspection units. Each chamber lowers to enclose the bottle in a sealed, fixed-volume cavity.

Inside the chamber, the testing system measures vacuum levels and monitors any pressure changes over time. A pressure drop that exceeds the allowed threshold indicates a potential leak, such BFS containers are automatically removed from the line. Accepted products continue smoothly to the next stage.

Tailored for high-throughput production lines, this leak testing solution can be integrated directly into existing setups, helping maintain both speed and quality without compromising container integrity.

Principle of Vacuum Decay Leak Testing
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Inspection Equipment
Visual Inspection Machines
Visual Inspection Machines
Leak Testing Machines
Leak Testing Machines
Visual Inspection & Leak Testing Machine
Visual Inspection & Leak Testing Machine
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Products
  • Visual Inspection Machines
  • Leak Testing Machines
  • Visual Inspection & Leak Testing Machine
Test Methods
  • Visual Image Processing
  • Vacuum Decay
  • High Voltage Leak Detection (HVLD)
Applications
  • Liquid Dosage
  • Freeze-Dried Powder
Contact Us
zzoneinspection@gmail.com
+86-731-88906436
+86-18692213322 (Sabrina Wang)
+86-13786180170 (Cici Li)